Mostrant de 1 a 7 de 7 notícies disponibles amb etiqueta "obesity"
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Recently published research article in collaboration with Dr. Jacques Behmoaras from the Imperial College of London
Highlights
Cyp2j4 deletion in rats offers a simplified genetic landscape as opposed to the mice locus, which is under significant allelic expansion.
Under different metabolic stresses (aging, cafeteria diet), Cyp2j4−/− rats show an accelerated adipogenesis, which progress towards adipocyte dysfunction.
Adipocyte dysfunction in Cyp2j4−/− rats under cafeteria diet (CAF) is characterised by down-regulation of white adipose tissue (WAT) PPARγ and C/EBPα, adipocyte hypertrophy and extracellular matrix remodeling.
Cyp2j4−/− rats treated with CAF display exacerbated weight gain, insulin resistance, hepatic lipid accumulation and dysregulated gluconeogenesis.
Cyp2j4−/− rats display alternative arachidonic acid pathway usage in their adipose tissue upon CAF and aging.
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Recently published review paper in Trends in Food Science & Technology
Strategy for limiting food intake using food components aimed at multiple targets in the gastrointestinal tract
Joan Serrano, Angela Casanova-Martí, M. Teresa Blay, Ximena Terra, Montserrat Pinent*, Anna ArdevolIn this work we review the bioactivity of various food-related compounds for different functions of the gastrointestinal tract finally suggesting that an integrative approach based on the modulation of multiple targets with foods could help to limit food intake.
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Toni Olona has started his PhD in the Imperial College, London, UK in collaboration with MoBioFood Research Group
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MoBioFood published a book chapter describing the flavonoid interaction with the gastrointestinal tract
The book is entitled "Grape Seeds: Nutrient Content, Antioxidant Properties and Health Benefits". Nova Publishers New York.
Chapter 3: Flavonoids Interaction with Gastrointestinal Tract: Modulation of Enteroendocrine System, Intestinal Permeability and Metabolic Endotoxemia.
This chapter is focused on how flavonoids could modulate the body homeostasis acting directly on the gastrointestinal tract, explaining their effects on obesity-related pathologies.
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Recently accepted paper in the Journal of Molecular Endocrinology: "Leptin signal transduction underlies the differential metabolic response of LEW and WKY rats to cafeteria diet"
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Research collaboration between MoBioFood and the Imperial College from London
During the last week, Dr Jacques Behmoaras and Jeong Hun Ko from the Imperial College, London, UK have visited our lab at the MoBioFood Research Group, URV, Spain due to a research collaboration.
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MoBioFood Research Group ha publicat recentment un treball al Journal of Functional Foods
Mobiofood Research Group ha publicat recentment un treball al Journal of Functional Foods que descriu l'efecte antiinflamatori i immunoestimulador de les proantocianidines de llavor de raïm conjuntament amb el DHA
N Martínez-Micaelo, N González-Abuín, M Pinent, A Ardévol and M Blay. Procyanidins and docosahexaenoic acid suppress inflammation and boost immune system in cafeteria diet-fed rats. Journal of Functional Foods (2015), pp. 61-71. DOI information: 10.1016/j.jff.2015.02.017
