llistat de les publicacions dels membres estables | Grup de recerca MoBioFood

Darrera actualització: 3 de desembre 2024

Syntheses of differentially fluorinated triazole-based 1-deoxysphingosine analogues en route to SphK inhibitors.

Cardona A, Ivanova V, Beltrán-Debón R, Barril X, Castillón S, Díaz Y, Matheu MI. Org Biomol Chem. 2024 Nov 20. doi: 10.1039/d4ob01656d. Online ahead of print. PMID: 39565065

Vols conèixer una font de proteïna sostenible i nutricionalment equivalent a la proteïna d'origen animal?.Descamps-Solà M,, Segú H, Vilalta A, Valls-

Bautista C, Rodríguez-Gallego E. Ciències 48 (2024). https://doi.org/10.5565/rev/ciencies.491

Profiling bitter taste receptors (TAS2R) along the gastrointestinal tract and their influence on enterohormone secretion. Gender- and age-related effects in the colon.

Jalševac F, Descamps-Solà M, Grau-Bové C, Segú H, Auguet T, Avilés-Jurado FX, Balaguer F, Jorba R, Beltrán-Debón R, Blay MT, Terra Barbadora X, Pinent M, Ardévol A. Front Endocrinol (Lausanne). 2024 Oct 17;15:1436580. doi: 10.3389/fendo.2024.1436580. eCollection 2024. PMID: 39512758 Free PMC article.

Transcriptional expression of SLC16A7 as a biomarker of occult lymph node metastases in patients with head and neck squamous cell carcinoma.

Camacho M, Vázquez-López C, Valero C, Holgado A, Terra X, Avilés-Jurado FX, León X. Eur Arch Otorhinolaryngol. 2024 Dec;281(12):6637-6644. doi: 10.1007/s00405-024-08882-9. Epub 2024 Aug 31. PMID: 39215860

Intestinal Taste Receptor Expression and Its Implications for Health: An Integrative Analysis in Female Rats after Chronic Insect Supplementation.

Segú H, Jalševac F, Lores M, Beltrán-Debón R, Terra X, Pinent M, Ardévol A, Rodríguez-Gallego E, Blay MT. J Agric Food Chem. 2024 Jun 10;72(24):13929-42. doi: 10.1021/acs.jafc.4c02408. Online ahead of print. PMID: 38857423 Free PMC article.

Multi-tissue profiling of oxylipins reveal a conserved up-regulation of epoxide:diol ratio that associates with white adipose tissue inflammation and liver steatosis in obesity.

Hateley C, Olona A, Halliday L, Edin ML, Ko JH, Forlano R, Terra X, Lih FB, Beltrán-Debón R, Manousou P, Purkayastha S, Moorthy K, Thursz MR, Zhang G, Goldin RD, Zeldin DC, Petretto E, Behmoaras J. EBioMedicine. 2024 May;103:105127. doi: 10.1016/j.ebiom.2024.105127. Epub 2024 Apr 26. PMID: 38677183 Free PMC article.

Positive impact of early-probiotic administration on performance parameters, intestinal health and microbiota populations in broiler chickens.

Hussain M, Aizpurua O, Pérez de Rozas A, París N, Guivernau M, Jofré A, Tous N, Ng'ang'a ZW, Alberdi A, Rodríguez-Gallego E, Kogut MH, Tarradas J. Poult Sci. 2024 Oct 10;103(12):104401. doi: 10.1016/j.psj.2024.104401. Online ahead of print. PMID: 39489036 Free PMC article.

Assessing the impact of insect protein sources on intestinal health and disease: insights from human ex vivo and rat in vivo models.

Segú H, Jalševac F, Sierra-Cruz M, Feliu F, Movassat J, Rodríguez-Gallego E, Terra X, Pinent M, Ardévol A, Blay MT. Food Funct. 2024 Apr 22;15(8):4552-4563. doi: 10.1039/d4fo00381k. PMID: 38584501

Survivin/BIRC5 as a novel molecular effector at the crossroads of glucose metabolism and radioresistance in head and neck squamous cell carcinoma.

Benaiges E, Ceperuelo-Mallafré V, Guaita S, Maymó-Masip E, Madeira A, Gómez D, Hernández V, Vilaseca I, Merma C, León X, Terra X, Vendrell J, Avilés-Jurado FX, Fernández-Veledo S. Head Neck. 2024 Jul;46(7):1752-1765. doi: 10.1002/hed.27651. Epub 2024 Feb 2. PMID: 38305029

Molecular Adaptations of BDNF/NT-4 Neurotrophic and Muscarinic Pathways in Ageing Neuromuscular Synapses.

Balanyà-Segura M, Polishchuk A, Just-Borràs L, Cilleros-Mañé V, Silvera C, Ardévol A, Tomàs M, Lanuza MA, Hurtado E, Tomàs J. Int J Mol Sci. 2024 Jul 23;25(15):8018. doi: 10.3390/ijms25158018. PMID: 39125587 Free PMC article.

Bitter taste receptors along the gastrointestinal tract: comparison between humans and rodents.

Descamps-Solà M, Vilalta A, Jalsevac F, Blay MT, Rodríguez-Gallego E, Pinent M, Beltrán-Debón R, Terra X, Ardévol A. Front Nutr. 2023 Aug 30;10:1215889. doi: 10.3389/fnut.2023.1215889. eCollection 2023. PMID: 37712001 Free PMC article. Review.

Assessing the impact of insect protein sources on intestinal health and disease: insights from human ex vivo and rat in vivo models

Helena Segú, Florijan Jalševac, Marta Sierra-Cruz, Francesc Feliu, Jamileh Movassat, Esther Rodríguez-Gallego, Ximena Terra, Montserrat Pinent, Anna Ardévol and M. Teresa Blay. Food Funct., 2024, 15, 4552.

Relationship between transcriptional expression of pyruvate dehydrogenase and local control of disease in patients with oral cavity carcinomas.

León X, Bagué S, Holgado A, Quer M, Terra X, Camacho M, Avilés-Jurado FX. Acta Otorrinolaringol Esp (Engl Ed). 2023 Nov-Dec;74(6):372-378. doi: 10.1016/j.otoeng.2023.05.006. Epub 2023 Sep 18. PMID: 37730160.

Bitter taste receptors along the gastrointestinal tract: comparison between humans and rodents.

Descamps-Solà M, Vilalta A, Jalsevac F, Blay MT, Rodríguez-Gallego E, Pinent M, Beltrán-Debón R, Terra X, Ardévol A. Front Nutr. 2023 Aug 30;10:1215889. doi: 10.3389/fnut.2023.1215889. PMID: 37712001; PMCID: PMC10498470.

Inhibition of DPP-IV Activity and Stimulation of GLP-1 Release by Gastrointestinally Digested Black Soldier Fly Prepupae.

Luparelli AV, Miguéns-Gómez A, Ardévol A, Sforza S, Caligiani A, Pinent M. Foods. 2023 May 17;12(10):2027. doi: 10.3390/foods12102027. PMID: 37238845; PMCID: PMC10217252.

GSPE Pre-Treatment Exerts Long-Lasting Preventive Effects against Aging-Induced Changes in the Colonic Enterohormone Profile of Female Rats.

Miguéns-Gómez A, Sierra-Cruz M, Blay MT, Rodríguez-Gallego E, Beltrán-Debón R, Terra X, Pinent M, Ardévol A. Int J Mol Sci. 2023 Apr 25;24(9):7807. doi: 10.3390/ijms24097807. PMID: 37175514; PMCID: PMC10177949.

GSPE pre-treatment protects against long-term cafeteria diet-induced mitochondrial and inflammatory affectations in the hippocampus of rats.

Busquets O, Carrasco M, Espinosa-Jiménez T, Ettcheto M, Verdaguer E, Auladell C, Bullò M, Camins A, Pinent M, Rodríguez-Gallego E, Folch J.Nutr Neurosci. 2022 Dec;25(12):2627-2637. doi: 10.1080/1028415X.2021.1995118. Epub 2021 Nov 18. PMID: 34789070.

Administration of Alphitobius diaperinus or Tenebrio molitor before meals transiently increases food intake through enterohormone regulation in female rats.

Miguéns-Gómez A, Sierra-Cruz M, Segú H, Beltrán-Debón R, Rodríguez-Gallego E, Terra X, Blay MT, Pérez-Vendrell AM, Pinent M, Ardévol A. J Sci Food Agric. 2022 Nov 2. doi: 10.1002/jsfa.12305. Online ahead of print. PMID: 36324158

Prognostic capacity of the transcriptional expression of lactate dehydrogenase A in patients with head and neck squamous cell carcinoma.

Bagué S, León X, Terra X, Lejeune M, Camacho M, Avilés-Jurado FX. Head Neck. 2022 Nov;44(11):2505-2512. doi: 10.1002/hed.27161. Epub 2022 Aug 4. PMID: 36207788

Differential effects of a cafeteria diet and GSPE preventive treatments on the enterohormone secretions of aged vs. young female rats.

Miguéns-Gómez A, Sierra-Cruz M, Pérez-Vendrell AM, Rodríguez-Gallego E, Beltrán-Debón R, Terra X, Ardévol A, Pinent M. Food Funct. 2022 Oct 17;13(20):10491-10500. doi: 10.1039/d2fo02111k. PMID: 36148543

Molecular composition of lipid and protein fraction of almond, beef and lesser mealworm after in vitro simulated gastrointestinal digestion and correlation with the hormone-stimulating properties of the digesta.

Accardo F, Miguéns-Gómez A, Lolli V, Faccini A, Ardévol A, Terra X, Caligiani A, Pinent M, Sforza S. Food Res Int. 2022 Aug;158:111499. doi: 10.1016/j.foodres.2022.111499. Epub 2022 Jun 18. PMID: 35840211.

Intestinal Morphometric Changes Induced by a Western-Style Diet in Wistar Rats and GSPE Counter-Regulatory Effect. Nutrients.

Segú H, Jalševac F, Pinent M, Ardévol A, Terra X, Blay MT. 2022 Jun 23;14(13):2608. doi: 10.3390/nu14132608. PMID: 35807788; PMCID: PMC9268310.

Semaphorin-3F/Neuropilin-2 Transcriptional Expression as a Predictive Biomarker of Occult Lymph Node Metastases in HNSCC.

Meler-Claramonte C, Avilés-Jurado FX, Vilaseca I, Terra X, Bragado P, Fuster G, León Vintró X, Camacho M. 2022 Apr 30;14(9):2259. doi: 10.3390/cancers14092259. PMID: 35565388; PMCID: PMC9100497.

Editorial: Insects as Food and Feed.

Meyer-Rochow VB, Pinent M, Costa Neto EM, Grabowski NT, Fratini F, Mancini S.Front Vet Sci. 2022 Mar 29;9:873765. doi: 10.3389/fvets.2022.873765. eCollection 2022. PMID: 35425834 Free PMC article. No abstract available.

GLP1 Exerts Paracrine Activity in the Intestinal Lumen of Human Colon.

Grau-Bové C, González-Quilen C, Cantini G, Nardini P, Espina B, Bani D, Terra X, Blay M, Rodríguez-Gallego E, Luconi M, Ardévol A, Pinent M. Int J Mol Sci. 2022 Mar 24;23(7):3523. doi: 10.3390/ijms23073523. PMID: 35408884 Free PMC article.

Effect of an Acute Insect Preload vs. an Almond Preload on Energy Intake, Subjective Food Consumption and Intestinal Health in Healthy Young Adults.

Miguéns-Gómez A, Sierra-Cruz M, Rodríguez-Gallego E, Beltrán-Debón R, Blay MT, Terra X, Pinent M, Ardévol A. Nutrients. 2022 Mar 31;14(7):1463. doi: 10.3390/nu14071463. PMID: 35406076 Free PMC article.

Application of emerging technologies to obtain legume protein isolates with improved techno-functional properties and health effects.

Bou R, Navarro-Vozmediano P, Domínguez R, López-Gómez M, Pinent M, Ribas-Agustí A, Benedito JJ, Lorenzo JM, Terra X, García-Pérez JV, Pateiro M, Herrera-Cervera JA, Jorba-Martín R.Compr Rev Food Sci Food Saf. 2022 May;21(3):2200-2232. doi: 10.1111/1541-4337.12936. Epub 2022 Mar 26. PMID: 35340098 Free article. Review.

Resistin and IL-15 as Predictors of Invasive Mechanical Ventilation in COVID-19 Pneumonia Irrespective of the Presence of Obesity and Metabolic Syndrome.
Perpiñan C, Bertran L, Terra X, Aguilar C, Binetti J, Lopez-Dupla M, Rull A, Reverté L, Yeregui E, Gómez-Bertomeu F, Peraire J, Auguet T, On Behalf Of Covid-Study Group. J Pers Med. 2022 Mar 3;12(3):391. doi: 10.3390/jpm12030391. PMID: 35330391 Free PMC article.
The Hidden One: What We Know About Bitter Taste Receptor 3 9.

Jalševac F, Terra X, Rodríguez-Gallego E, Beltran-Debón R, Blay MT, Pinent M, Ardévol A. 2022 Mar 8;13:854718. doi: 10.3389/fendo.2022.854718. PMID: 35345470; PMCID: PMC8957101.

Revealing 2-dimethylhydrazino-2-alkyl alkynyl sphingosine derivatives as sphingosine kinase 2 inhibitors: Some hints on the structural basis for selective inhibition.

Corro-Morón M, Granell A, Ivanova V, Domingo E, Beltrán-Debón R, Barril X, Sanz MJ, Matheu MI, Castillón S, Díaz Y.Bioorg Chem. 2022 Apr;121:105668. doi: 10.1016/j.bioorg.2022.105668. Epub 2022 Feb 12. PMID: 35219046 Free article.

Functional and genomic comparative study of the bitter taste receptor family TAS2R: Insight into the role of human TAS2R5.

Grau-Bové C, Grau-Bové X, Terra X, Garcia-Vallve S, Rodríguez-Gallego E, Beltran-Debón R, Blay MT, Ardévol A, Pinent M.FASEB J. 2022 Mar;36(3):e22175. doi: 10.1096/fj.202101128RR. PMID: 35107858

Lipocalin, Resistin and Gut Microbiota-Derived Propionate Could Be Used to Predict Metabolic Bariatric Surgery Selected Outcomes

Auguet, T; Lopez-Dupla, M; Ramos, J; Bertran, L; Riesco, D; Aguilar, C; Ardevol, A; Pinent, M; Sabench, F; Del Castillo, D Richart, C.Processes 2022, 10(1), 143; https://doi.org/10.3390/pr10010143

Glucagon-like peptide-1 regulation by food proteins and protein hydrolysates.

Miguéns-Gómez A, Casanova-Martí À, Blay MT, Terra X, Beltrán-Debón R, Rodríguez-Gallego E, Ardévol A, Pinent M. Nutr Res Rev. 2021 Dec;34(2):259-275. doi: 10.1017/S0954422421000019. Epub 2021 Jan 19. PMID: 33461642 Review.

GSPE pre-treatment protects against long-term cafeteria diet-induced mitochondrial and inflammatory affectations in the hippocampus of rats.

Busquets O, Carrasco M, Espinosa-Jiménez T, Ettcheto M, Verdaguer E, Auladell C, Bullò M, Camins A, Pinent M, Rodríguez-Gallego E, Folch J. Nutritional Neuroscience, https://doi-org.sabidi.urv.cat/10.1080/1028415X.2021.1995118

Identification of Broad-Spectrum MMP Inhibitors by Virtual Screening.

Gimeno A, Cuffaro D, Nuti E, Ojeda-Montes MJ, Beltrán-Debón R, Mulero M, Rossello A, Pujadas G, Garcia-Vallvé S.Molecules. 2021 Jul 28;26(15):4553. doi: 10.3390/molecules26154553. PMID: 34361703

Grape-Seed Proanthocyanidin Extract Reverts Obesity-Related Metabolic Derangements in Aged Female Rats.

Sierra-Cruz M, Miguéns-Gómez A, Grau-Bové C, Rodríguez-Gallego E, Blay M, Pinent M, Ardévol A, Terra X, Beltrán-Debón R.Nutrients. 2021 Jun 16;13(6):2059. doi: 10.3390/nu13062059. PMID: 34208508

Circulating microRNAs modulating glycolysis as non-invasive prognostic biomarkers of HNSCC.

Avilés-Jurado FX, Muñoz C, Meler C, Flores JC, Gumà J, Benaiges E, Mora J, Camacho M, León X, Vilaseca I, Terra X. Eur ArchOtorhinolaryngol. 2021 May;278(5):1585-1594. doi: 10.1007/s00405-020-06240-z. Epub 2020 Jul 31. PMID: 32737645

Anti-Inflammatory and Immunomodulatory Effects of the Grifola frondosa Natural Compound o-Orsellinaldehyde on LPS-Challenged Murine Primary Glial Cells. Roles of NF-κβ and MAPK.

Tomas-Hernandez S, Blanco J, Garcia-Vallvé S, Pujadas G, Ojeda-Montes MJ, Gimeno A, Arola L, Minghetti L, Beltrán-Debón R, Mulero M.Pharmaceutics. 2021 May 28;13(6):806. doi: 10.3390/pharmaceutics13060806.

Succinate Pathway in Head and Neck Squamous Cell Carcinoma: Potential as a Diagnostic and Prognostic Marker.

Terra X, Ceperuelo-Mallafré V, Merma C, Benaiges E, Bosch R, Castillo P, Flores JC, León X, Valduvieco I, Basté N, Cámara M, Lejeune M, Gumà J, Vendrell J, Vilaseca I, Fernández-Veledo S, Avilés-Jurado FX.Cancers (Basel). 2021 Apr 1;13(7):1653. doi: 10.3390/cancers13071653. PMID: 33916314 Free PMC article.

Glucagon Shows Higher Sensitivity than Insulin to Grapeseed Proanthocyanidin Extract (GSPE) Treatment in Cafeteria-Fed Rats.

Grau-Bové C, Ginés I, Beltrán-Debón R, Terra X, Blay M, Pinent M, Ardévol A.Nutrients. 2021 Mar 26;13(4):1084. doi: 10.3390/nu13041084.PMID: 33810265 Free article.

Predictive Biomarkers of COVID-19 Severity in SARS-CoV-2 Infected Patients with Obesity and Metabolic Syndrome.

Perpiñan C, Bertran L, Terra X, Aguilar C, Lopez-Dupla M, Alibalic A, Riesco D, Camaron J, Perrone F, Rull A, Reverté L, Yeregui E, Marti A, Vidal F, Auguet TJ. Pers Med. 2021 Mar 22;11(3):227. doi: 10.3390/jpm11030227.PMID: 33809913 Free PMC article.

The aspartate aminotransaminase/alanine aminotransaminase (De Ritis) ratio predicts sensitivity to radiotherapy in head and neck carcinoma patients.

Sansa A, Venegas MDP, Valero C, Pardo L, Avilés-Jurado FX, Terra X, Quer M, León X.Head Neck. 2021 Mar 6. doi: 10.1002/hed.26673. Online ahead of print.PMID: 33675096

Glucagon-like peptide-1 regulation by food proteins and protein hydrolysates.

Miguéns-Gómez A, Casanova-Martí À, Blay MT, Terra X, Beltrán-Debón R, Rodríguez-Gallego E, Ardévol A, Pinent M. Nutr Res Rev. 2021 Jan 19:1-17. doi: 10.1017/S0954422421000019. Online ahead of print.PMID: 33461642

Modulation of Food Intake by Differential TAS2R Stimulation in Rat.

Grau-Bové C, Miguéns-Gómez A, Gonzalez-Quilen, C, Fernández-López JA, Remesar X, Torres-Fuentes C, Ávila-Román J, Rodríguez-Gallego E, Beltrán-Debón R, Blay M, Terra X, Ardévol A, Pinent M.Nutrients. 2020;12(12):E3784. https://https://doi.org/10.3390/nu12123784. PMID: 33260866 Free article

Ten-Day Grape Seed Procyanidin Treatment Prevents Certain Ageing Processes in Female Rats over the Long Term.

Grau-Bové C, Sierra-Cruz M, Miguéns-Gómez A, Rodríguez-Gallego E, Beltrán-Debón R, Blay M, Terra X, Pinent M, Ardévol A.Nutrients. 2020 Nov 27;12(12):E3647. doi: 10.3390/nu12123647. PMID: 33260866 Free article.

Gastrointestinally Digested Protein from the Insect Alphitobius diaperinus Stimulates a Different Intestinal Secretome than Beef or Almond, Producing a Differential Response in Food Intake in Rats.

Miguéns-Gómez A, Grau-Bové C, Sierra-Cruz M, Jorba-Martín R, Caro A, Rodríguez-Gallego E, Beltrán-Debón R, Blay MT, Terra X, Ardévol A, Pinent M. Nutrients. 2020 Aug 7;12(8):2366. doi: 10.3390/nu12082366. PMID: 32784756 Free PMC article.

Long Term Exposure to a Grape Seed Proanthocyanidin Extract Enhances L-Cell Differentiation in Intestinal Organoids.

Casanova-Martí À, González-Abuín N, Serrano J, Blay MT, Terra X, Frost G, Pinent M, Ardévol A. Mol Nutr Food Res. 2020 Aug;64(16):e2000303. doi: 10.1002/mnfr.202000303. Epub 2020 Jul 8. PMID: 32613679

Effects of Flavanols on Enteroendocrine Secretion.

Grau-Bove, C.; Gonzalez-Quilen, C.; Terra, X.; Blay, M Teresa; Beltran-Debon, R.; Jorba-Martin, R.; Espina, B.; Pinent, M.; Ardevol, A. Biomolecules Volume: ‏ 10 Issue: ‏ 6 Published: ‏ 2020 Jun 01

Protective properties of grape-seed proanthocyanidins in human ex vivo acute colonic dysfunction induced by dextran sodium sulfate

Gonzalez-Quilen, C; Grau-Bove, C; Jorba-Martin, R; Caro-Tarrago, A; Pinent, M; Ardevol, A; Beltran-Debon, R ; Terra, X; Blay, MT. EUROPEAN JOURNAL OF NUTRITION 2020 Mar 18

Health-Promoting Properties of Proanthocyanidins for Intestinal Dysfunction.

González-Quilen C, Rodríguez-Gallego E, Beltrán-Debón R, Pinent M, Ardévol A, Blay MT, Terra X. Nutrients. 2020 Jan 2;12(1). pii: E130. doi: 10.3390/nu12010130. Review.

Long-Lasting Effects of GSPE on Ileal GLP-1R Gene Expression Are Associated with a Hypomethylation of the GLP-1R Promoter in Female Wistar Rats.

Ginés I, Gil-Cardoso K, D'Addario C, Falconi A, Bellia F, Blay MT, Terra X, Ardévol A, Pinent M, Beltrán-Debón R. Biomolecules. 2019 Dec 12;9(12). pii: E865. doi: 10.3390/biom9120865.

Proanthocyanidins Limit Adipose Accrual Induced by a Cafeteria Diet, Several Weeks after the End of the Treatment.

Ginés I, Gil-Cardoso K, Serrano J, Casanova-Marti À, Lobato M, Terra X, Blay MT, Ardévol A, Pinent M. Genes (Basel). 2019 Aug 8;10(8). pii: E598. doi: 10.3390/genes10080598.

Mining large databases to find new leads with low similarity to known actives: application to find new DPP-IV inhibitors.

Ojeda-Montes MJ, Casanova-Martí À, Gimeno A, Tomás-Hernández S, Cereto-Massagué A, Wolber G, Beltrán-Debón R, Valls C, Mulero M, Pinent M, Pujadas G, Garcia-Vallvé S. Future Med Chem. 2019 Jun;11(12):1387-1401. doi: 10.4155/fmc-2018-0597. Epub 2019 Jul 12.

Antihyperglycemic effect of a chicken feet hydrolysate via the incretin system: DPP-IV-inhibitory activity and GLP-1 release stimulation.

Casanova-Martí À, Bravo FI, Serrano J, Ardévol A, Pinent M, Muguerza B. Food Funct. 2019 Jun 21. doi: 10.1039/c9fo00695h. [Epub ahead of print]

Grape-Seed Proanthocyanidins are Able to Reverse Intestinal Dysfunction and Metabolic Endotoxemia Induced by a Cafeteria Diet in Wistar Rats.

González-Quilen C, Gil-Cardoso K, Ginés I, Beltrán-Debón R, Pinent M, Ardévol A, Terra X, Blay MT. Nutrients. 2019 Apr 29;11(5). pii: E979. doi: 10.3390/nu11050979

Grape Seed Proanthocyanidins Target the Enteroendocrine System in Cafeteria-Diet-Fed Rats.

Ginés I, Gil-Cardoso K, Terra X, Blay M, Pérez-Vendrell AM, Pinent M, Ardévol A. Mol Nutr Food Res. 2019 Apr 12:e1800912. doi: 10.1002/mnfr.201800912. [Epub ahead of print]

Protective Effect of Proanthocyanidins in a Rat Model of Mild Intestinal Inflammation and Impaired Intestinal Permeability Induced by LPS.

Gil-Cardoso K, Comitato R, Ginés I, Ardévol A, Pinent M, Virgili F, Terra X, Blay M. Mol Nutr Food Res. 2019 Jan 17:e1800720. doi: 10.1002/mnfr.201800720. [Epub ahead of print]

The co-administration of proanthocyanidins and an obesogenic diet prevents the increase in intestinal permeability and metabolic endotoxemia derived to the diet.

Gil-Cardoso K, Ginés I, Pinent M, Ardévol A, Blay M, Terra X. J Nutr Biochem. 2018 Dec;62:35-42. doi: 10.1016/j.jnutbio.2018.07.012. Epub 2018 Aug 30.

A novel ex vivo experimental setup to investigate how food components stimulate the enteroendocrine secretions of different intestinal segments.

Ginés I, Gil-Cardoso K, Robles P, Arola L, Terra X, Blay M, Ardévol A, Pinent M. J Agric Food Chem. 2018 Aug 27. doi: 10.1021/acs.jafc.8b03046. [Epub ahead of print]

Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesis.

Olona A, Terra X, Ko JH, Grau-Bové C, Pinent M, Ardevol A, Diaz AG, Moreno-Moral A, Edin M, Bishop-Bailey D, Zeldin DC, Aitman TJ, Petretto E, Blay M, Behmoaras J. Mol Metab. 2018 May;11:18-32. doi: 10.1016/j.molmet.2018.03.003. Epub 2018 Mar 9.

Effects of an Intermittent Grape-Seed Proanthocyanidin (GSPE) Treatment on a Cafeteria Diet Obesogenic Challenge in Rat

Ginés I, Gil-Cardoso K, Serrano J, Casanova-Martí À, Blay MT, Pinent M, Ardévol A, Terra X. Nutrients 2018, 10(3), 315; doi:10.3390/nu10030315 (registering DOI)

Grape seed proanthocyanidins influence gut microbiota and enteroendocrine secretions in female rats.

Casanova-Martí À, Serrano J, Portune KJ, Sanz Y, Blay MT, Terra X, Ardévol A, Pinent M. Food Funct. 2018 Feb 23. doi: 10.1039/c7fo02028g. [Epub ahead of print]

Prognostic relevance of insulin resistance on disease-free survival in head and neck squamous cell carcinomas: Preliminary results.

Avilés-Jurado FX, Flores JC, Gumà J, Ceperuelo-Mallafré V, Casanova-Marqués R, Gómez D, Vendrell JJ, León X, Vilaseca I, Terra X. Head Neck. 2017 Dec;39(12):2501-2511. doi: 10.1002/hed.24919. Epub 2017 Sep 30

Strategy for limiting food intake using food components aimed at multiple targets in the gastrointestinal tract.

Serrano J, Casanova-Martí À, Blay MT, Terra X, Pinent M, Ardévol A.Trends in Food Science & Technology. 2017 Oct; 68: 113-129. doi: 10.1016/j.tifs.2017.08.002

Acute selective bioactivity of grape seed proanthocyanidins on enteroendocrine secretions in the gastrointestinal tract.

Casanova-Martí À, Serrano J, Blay MT, Terra X, Ardévol A, Pinent M.Food Nutr Res. 2017 Jun 7; 61(1): 1321347. doi: 10.1080/16546628.2017.1321347. eCollection 2017.

Chronic supplementation with dietary proanthocyanidins protects from diet-induced intestinal alterations in obese rats.

Gil-Cardoso K, Ginés I, Pinent M, Ardévol A, Arola L, Blay M, Terra X. Mol Nutr Food Res. 2017 Feb 20; 61(8): 1601039. doi: 10.1002/mnfr.201601039. [Epub ahead of print]

A cafeteria diet triggers intestinal inflammation and oxidative stress in obese rats.

Gil-Cardoso K, Ginés I, Pinent M, Ardévol A, Terra X, Blay M. Br J Nutr. 2017 Jan;117(2):218-229. doi: 10.1017/S0007114516004608. Epub 2017 Jan 30.

Effects of flavonoids on intestinal inflammation, barrier integrity and changes in gut microbiota during diet-induced obesity.

Gil-Cardoso K, Ginés I, Pinent M, Ardévol A, Blay M, Terra X. Nutr Res Rev. 2016 Nov; 14:1-15. doi: 10.1017/S0954422416000159 [Epub ahead of print]

Effects of flavanols on the enteroendocrine system: Repercussions on food intake.

Pinent M, Blay M, Serrano J, Ardévol A. Crit Rev Food Sci Nutr. 2017 Jan 22;57(2):326-334. doi: 10.1080/10408398.2013.871221.

Defining Conditions for Optimal Inhibition of Food Intake in Rats by a Grape-Seed Derived Proanthocyanidin Extract.

Serrano J, Casanova-Martí À, Blay M, Terra X, Ardévol A, Pinent M. Nutrients. 2016 Oct 20;8(10). pii: E652. doi: 10.3390/nu8100652.

Identification of a nutrient-sensing transcriptional network in monocytes by using inbred rat models on a cafeteria diet.

Martínez-Micaelo N, González-Abuín N, Terra X, Ardévol A, Pinent M, Petretto E, Behmoaras J, Blay M. Dis Model Mech. 2016 Oct 1;9(10):1231-1239. doi: 10.1242/dmm.025528.

Subchronic treatment with grape-seed phenolics inhibits ghrelin production despite a short-term stimulation of ghrelin secretion produced by bitter-sensing flavanols.

Serrano J, Casanova-Martí À, Depoortere I, Blay MT, Terra X, Pinent M, Ardévol A.Mol Nutr Food Res. 2016 Jul 15; 60(12): 2554-2564. doi: 10.1002/mnfr.201600242. [Epub ahead of print]

Dietary fatty acid composition is sensed by the NLRP3 inflammasome: omega-3 fatty acid (DHA) prevents NLRP3 activation in human macrophages.

Martínez-Micaelo N, González-Abuín N, Pinent M, Ardévol A, Blay M.Food Funct. 2016 Aug 10;7(8):3480-7. doi: 10.1039/c6fo00477f.

A specific dose of grape seed-derived proanthocyanidins to inhibit body weight gain limits food intake and increases energy expenditure in rats.

Serrano J, Casanova-Martí À, Gual A, Pérez-Vendrell AM, Blay MT, Terra X, Ardévol A, Pinent M. Eur J Nutr. 2016 Apr 2; 56(4): 1629-1636. doi: 10.1007/s00394-016-1209-x. [Epub ahead of print]

External validation of sTWEAK as a prognostic noninvasive biomarker for head and neck squamous cell carcinoma.

Terra X, Gómez D, García-Lorenzo J, Flores JC, Figuerola E, Mora J, Chacón MR, Quer M, Camacho M, León X, Avilés-Jurado FX.Head Neck. 2016 Apr;38 Suppl 1:E1358-63. doi: 10.1002/hed.24227.

Acutely administered grape-seed proanthocyanidin extract acts as a satiating agent.

Serrano J, Casanova-Martí À, Gil-Cardoso K, Blay MT, Terra X, Pinent M, Ardévol A.Food Funct. 2016 Jan;7(1):483-90. doi: 10.1039/c5fo00892a.

Leptin signal transduction underlies the differential response of LEW and WKY rats to cafeteria diet.

Martínez-Micaelo N, González-Abuín N, Ardévol A, Pinent M, Petretto E, Behmoaras J, Blay M. J Mol Endocrinol. 2016 Jan;56(1):1-10. doi: 10.1530/JME-15-0089.

Antioxidant effects of proanthocyanidin-rich natural extracts from grape seed and cupuassu on gastrointestinal mucosa.

Pinent M, Castell-Auví A, Genovese MI, Serrano J, Casanova A, Blay M, Ardévol A. J Sci Food Agric. 2016 Jan 15;96(1):178-82. doi: 10.1002/jsfa.7079.

Procyanidins and docosahexaenoic acid suppress inflammation and boost immune system in cafeteria diet-fed rats

Martinez-Micaelo N, González-Abuín N, Mulero M, Pinent M, Ardévol A, Blay M. Journal Of Functional Foods. 2015 May; 15: 61-67. doi: 10.1016/j.jff.2015.02.017

Procyanidin B2 inhibits inflammasome-mediated IL-1β production in lipopolysaccharide-stimulated macrophages

Martinez-Micaelo N, González-Abuín N, Pinent M, Ardévol A, Blay M. Mol Nutr Food Res. 2015 Feb;59(2):262-9. doi: 10.1002/mnfr.201400370. Epub 2014 Dec 5

Procyanidins and their healthy protective effects against type 2 diabetes.

Gonzalez-Abuin N, Pinent M, Casanova-Marti A, Arola L, Blay M, Ardevol A. Curr Med Chem. 2015;22(1):39-50. doi: 10.2174/0929867321666140916115519.

Prostacyclin-synthase expression in head and neck carcinoma patients and its prognostic value in the response to radiotherapy.

Camacho M, Piñeiro Z, Alcolea S, García J, Balart J, Terra X, Avilés-Jurado FX, Soler M, Quer M, León X, Vila L. J Pathol. 2015 Jan;235(1):125-35. doi: 10.1002/path.4453.

Procyanidin B₂ inhibits inflammasome-mediated IL-1β production in lipopolysaccharide-stimulated macrophages.

Martinez-Micaelo N, González-Abuín N, Pinent M, Ardévol A, Blay M. Mol Nutr Food Res. 2015 Feb;59(2):262-9. doi: 10.1002/mnfr.201400370.

Downregulation of lipogenesis and fatty acid oxidation in the subcutaneous adipose tissue of morbidly obese women.

Auguet T, Guiu-Jurado E, Berlanga A, Terra X, Martinez S, Porras JA, Ceausu A, Sabench F, Hernandez M, Aguilar C, Sirvent JJ, Del Castillo D, Richart C.Obesity (Silver Spring). 2014 Sep;22(9):2032-8. doi: 10.1002/oby.20809.

Endocannabinoid receptors gene expression in morbidly obese women with nonalcoholic fatty liver disease.

Auguet T, Berlanga A, Guiu-Jurado E, Terra X, Martinez S, Aguilar C, Filiu E, Alibalic A, Sabench F, Hernández M, Del Castillo D, Richart C. Biomed Res Int. 2014;2014:502542. doi: 10.1155/2014/502542. Epub 2014 Apr 23.

Low blood levels of sTWEAK are related to locoregional failure in head and neck cancer.

Avilés-Jurado FX, Terra X, Gómez D, Flores JC, Raventós A, Maymó-Masip E, León X, Serrano-Gonzalvo V, Vendrell J, Figuerola E, Chacón MR. Eur Arch Otorhinolaryngol. 2014 May 26; 272(7):1733-41. doi: 10.1007/s00405-014-3095-2

Chronic intake of proanthocyanidins and docosahexaenoic acid improves skeletal muscle oxidative capacity in diet-obese rats.

Casanova E, Baselga-Escudero L, Ribas-Latre A, Cedó L, Arola-Arnal A, Pinent M, Bladé C, Arola L, Salvadó MJ. J Nutr Biochem. 2014 Oct;25(10):1003-10. doi: 10.1016/j.jnutbio.2014.05.003. Epub 2014 Jun 5.

A grape seed extract increases active glucagon-like peptide-1 levels after an oral glucose load in rats.

González-Abuín N, Martínez-Micaelo N, Margalef M, Blay M, Arola-Arnal A, Muguerza B, Ardévol A, Pinent M. Food Funct. 2014 Sep;5(9):2357-64. doi: 10.1039/c4fo00447g.

Effect of the co-occurring olive oil and thyme extracts on the phenolic bioaccessibility and bioavailability assessed by in vitro digestion and cell models.

Rubió L, Macià A, Castell-Auví A, Pinent M, Blay MT, Ardévol A, Romero MP, Motilva MJ. Food Chem. 2014 Apr 15;149:277-84. doi: 10.1016/j.foodchem.2013.10.075. Epub 2013 Oct 30.

Grape-seed procyanidins modulate cellular membrane potential and nutrient-induced GLP-1 secretion in STC-1 cells.

González-Abuín N, Martínez-Micaelo N, Blay M, Green BD, Pinent M, Ardévol A. Am J Physiol Cell Physiol. 2014 Mar 1;306(5):C485-92. doi: 10.1152/ajpcell.00355.2013. Epub 2013 Dec 26.

Grape-seed procyanidins prevent the cafeteria-diet-induced decrease of glucagon-like peptide-1 production.

González-Abuín N, Martínez-Micaelo N, Blay M, Ardévol A, Pinent M. J Agric Food Chem. 2014 Feb 5;62(5):1066-72. doi: 10.1021/jf405239p. Epub 2014 Jan 22.

Gallic acid is an active component for the anticarcinogenic action of grape seed procyanidins in pancreatic cancer cells.

Cedó L, Castell-Auví A, Pallarès V, Macià A, Blay M, Ardévol A, Motilva MJ, Pinent M. Nutr Cancer. 2014;66(1):88-96. doi: 10.1080/01635581.2014.851714. Epub 2013 Dec 10.

Grape Seed Procyanidin Extract Improves Insulin Production but Enhances Bax Protein Expression in Cafeteria-Treated Male Rats.

Cedó L, Castell-Auví A, Pallarès V, Blay M, Ardévol A, Pinent M. Int J Food Sci. 2013;2013:875314. doi: 10.1155/2013/875314

Effects of grape seed procyanidin extract over low-grade chronic inflammation of obese Zucker fa/fa rats

Pallarès V, Cedó L, Castell-Auví A, Pinent M, Ardévol A, Arola L, Blay M. Food Research International. 2013; 51(1): 319-324. doi: 10.1016/j.foodres.2013.05.006.

Adipocytokine levels in women with anorexia nervosa. Relationship with weight restoration and disease duration.

Terra X, Auguet T, Agüera Z, Quesada IM, Orellana-Gavaldà JM, Aguilar C, Jiménez-Murcia S, Berlanga A, Guiu-Jurado E, Menchón JM, Fernández-Aranda F, Richart C. Int J Eat Disord. 2013 Dec;46(8):855-61. doi: 10.1002/eat.22166. Epub 2013 Jul 23.

Long-term changes in leptin, chemerin and ghrelin levels following different bariatric surgery procedures: Roux-en-Y gastric bypass and sleeve gastrectomy.

Terra X, Auguet T, Guiu-Jurado E, Berlanga A, Orellana-Gavaldà JM, Hernández M, Sabench F, Porras JA, Llutart J, Martinez S, Aguilar C, Del Castillo D, Richart C. Obes Surg. 2013 Nov;23(11):1790-8. doi: 10.1007/s11695-013-1033-9.

Clinical and adipocytokine changes after bariatric surgery in morbidly obese women.

Auguet T, Terra X, Hernández M, Sabench F, Porras JA, Orellana-Gavaldà JM, Llutart J, Guiu-Jurado E, Berlanga A, Martinez S, Aguilar C, Castillo DD, Richart C.Obesity (Silver Spring). 2014 Jan;22(1):188-94. doi: 10.1002/oby.20470. Epub 2013 Jul 23.

Retinol binding protein-4 circulating levels were higher in nonalcoholic fatty liver disease vs. histologically normal liver from morbidly obese women.

Terra X, Auguet T, Broch M, Sabench F, Hernández M, Pastor RM, Quesada IM, Luna A, Aguilar C, del Castillo D, Richart C. Obesity (Silver Spring). 2013 Jan;21(1):170-7. doi: 10.1002/oby.20233.

Liver lipocalin 2 expression in severely obese women with non alcoholic fatty liver disease.

Auguet T, Terra X, Quintero Y, Martínez S, Manresa N, Porras JA, Aguilar C, Orellana-Gavaldà JM, Hernández M, Sabench F, Lucas A, Pellitero S, Del Castillo D, Richart C. Exp Clin Endocrinol Diabetes. 2013 Feb;121(2):119-24. doi: 10.1055/s-0032-1331696. Epub 2013 Feb 20.

Plasma visfatin levels and gene expression in morbidly obese women with associated fatty liver disease.

Auguet T, Terra X, Porras JA, Orellana-Gavaldà JM, Martinez S, Aguilar C, Lucas A, Pellitero S, Hernández M, Del Castillo D, Richart C. Clin Biochem. 2013 Feb;46(3):202-8. doi: 10.1016/j.clinbiochem.2012.11.006.

Procyanidins target mesenteric adipose tissue in Wistar lean rats and subcutaneous adipose tissue in Zucker obese rat.

Ardévol A, Motilva MJ, Serra A, Blay M, Pinent M. Food Chem. 2013 Nov 1;141(1):160-6. doi: 10.1016/j.foodchem.2013.02.104. Epub 2013 Mar 7.

Grape seed procyanidin extract reduces the endotoxic effects induced by lipopolysaccharide in rats.

Pallarès V, Fernández-Iglesias A, Cedó L, Castell-Auví A, Pinent M, Ardévol A, Salvadó MJ, Garcia-Vallvé S, Blay M. Free Radic Biol Med. 2013 Jul;60:107-14. doi: 10.1016/j.freeradbiomed.2013.02.007. Epub 2013 Feb 21.

Grape seed procyanidins improve β-cell functionality under lipotoxic conditions due to their lipid-lowering effect.

Castell-Auví A, Cedó L, Pallarès V, Blay M, Pinent M, Ardévol A. J Nutr Biochem. 2013 Jun;24(6):948-53. doi: 10.1016/j.jnutbio.2012.06.015. Epub 2012 Sep 17.

Grape seed procyanidin extract modulates proliferation and apoptosis of pancreatic beta-cells.

Cedó L, Castell-Auví A, Pallarès V, Blay M, Ardévol A, Arola L, Pinent M. Food Chem. 2013 May 1;138(1):524-30. doi: 10.1016/j.foodchem.2012.10.088. Epub 2012 Nov 12.

Procyanidins modulate microRNA expression in pancreatic islets.

Castell-Auví A, Cedó L, Movassat J, Portha B, Sánchez-Cabo F, Pallarès V, Blay M, Pinent M, Ardévol A. J Agric Food Chem. 2013 Jan 16;61(2):355-63. doi: 10.1021/jf303972f. Epub 2013 Jan 4.

Comparison of chi-squared automatic interaction detection classification trees vs TNM classification for patients with head and neck squamous cell carcinoma.

Avilés-Jurado FX, Terra X, Figuerola E, Quer M, León X. Arch Otolaryngol Head Neck Surg. 2012 Mar;138(3):272-9. doi: 10.1001/archoto.2011.1448.

Overexpression of the nuclear factor-kappa B (p65) in association with local failure in patients with head and neck carcinoma undergong radiotherapy or chemoradiotherapy.

Quintana A, Avilés FX, Terra X, Alcolea S, Camacho M, Quer M, Vila L, León X. Head Neck. 2013 Mar;35(3):370-5. doi: 10.1002/hed.22979. Epub 2012 Mar 16.

Increased levels and adipose tissue expression of visfatin in morbidly obese women: the relationship with pro-inflammatory cytokines.

Terra X, Auguet T, Quesada I, Aguilar C, Luna AM, Hernández M, Sabench F, Porras JA, Martínez S, Lucas A, Pellitero S, Llutart J, del Castillo D, Richart C. Clin Endocrinol (Oxf). 2012 Nov;77(5):691-8. doi: 10.1111/j.1365-2265.2011.04327.x.

Pancreatic islet proteome profile in Zucker fatty rats chronically treated with a grape seed procyanidin extract.

Cedó L, Castell-Auví A, Pallarès V, Ubaida Mohien C, Baiges I, Blay M, Ardévol A, Pinent M. Food Chem. 2012 Dec 1;135(3):1948-56. doi: 10.1016/j.foodchem.2012.06.042. Epub 2012 Jun 29.

Procyanidins modify insulinemia by affecting insulin production and degradation.

Castell-Auví A, Cedó L, Pallarès V, Blay MT, Pinent M, Motilva MJ, Garcia-Vallvé S, Pujadas G, Maechler P, Ardévol A. J Nutr Biochem. 2012 Dec;23(12):1565-72. doi: 10.1016/j.jnutbio.2011.10.010. Epub 2012 Mar 22.

Enhanced anti-inflammatory effect of resveratrol and EPA in treated endotoxin-activated RAW 264.7 macrophages.

Pallarès V, Calay D, Cedó L, Castell-Auví A, Raes M, Pinent M, Ardévol A, Arola L, Blay M. Br J Nutr. 2012 Nov 14;108(9):1562-73. doi: 10.1017/S0007114511007057. Epub 2012 Jan 6.

The effects of a cafeteria diet on insulin production and clearance in rats.

Castell-Auví A, Cedó L, Pallarès V, Blay M, Ardévol A, Pinent M. Br J Nutr. 2012 Oct;108(7):1155-62. doi: 10.1017/S0007114511006623. Epub 2011 Dec 12.

Grape seed-derived procyanidins decrease dipeptidyl-peptidase 4 activity and expression.

González-Abuín N, Martínez-Micaelo N, Blay M, Pujadas G, Garcia-Vallvé S, Pinent M, Ardévol A. J Agric Food Chem. 2012 Sep 12;60(36):9055-61. doi: 10.1021/jf3010349. Epub 2012 Aug 30.

Procyanidins and inflammation: molecular targets and health implications.

Martinez-Micaelo N, González-Abuín N, Ardèvol A, Pinent M, Blay MT. Biofactors. 2012 Jul-Aug;38(4):257-65. doi: 10.1002/biof.1019. Epub 2012 Apr 16. Review.

Additive, antagonistic, and synergistic effects of procyanidins and polyunsaturated fatty acids over inflammation in RAW 264.7 macrophages activated by lipopolysaccharide.

Pallarès V, Calay D, Cedó L, Castell-Auví A, Raes M, Pinent M, Ardévol A, Arola L, Blay M. Nutrition. 2012 Apr;28(4):447-57. doi: 10.1016/j.nut.2011.07.027. Epub 2011 Dec 14.

Omega-3 docosahexaenoic acid and procyanidins inhibit cyclo-oxygenase activity and attenuate NF-κB activation through a p105/p50 regulatory mechanism in macrophage inflammation.

Martinez-Micaelo N, González-Abuín N, Terra X, Richart C, Ardèvol A, Pinent M, Blay M. Biochem J. 2012 Jan 15;441(2):653-63. doi: 10.1042/BJ20110967.

Procyanidins improve some disrupted glucose homoeostatic situations: an analysis of doses and treatments according to different animal models.

Pinent M, Cedó L, Montagut G, Blay M, Ardévol A. Crit Rev Food Sci Nutr. 2012;52(7):569-84. doi: 10.1080/10408398.2010.501533. Review.

Identification of PPARgamma partial agonists of natural origin (I): development of a virtual screening procedure and in vitro validation.

Guasch L, Sala E, Castell-Auví A, Cedó L, Liedl KR, Wolber G, Muehlbacher M, Mulero M, Pinent M, Ardévol A, Valls C, Pujadas G, Garcia-Vallvé S. PLoS One. 2012;7(11):e50816. doi: 10.1371/journal.pone.0050816. Epub 2012 Nov 30.

Identification of novel human dipeptidyl peptidase-IV inhibitors of natural origin (Part II): in silico prediction in antidiabetic extracts.

Guasch L, Sala E, Ojeda MJ, Valls C, Bladé C, Mulero M, Blay M, Ardévol A, Garcia-Vallvé S, Pujadas G. PLoS One. 2012;7(9):e44972. doi: 10.1371/journal.pone.0044972. Epub 2012 Sep 21.

Identification of novel human dipeptidyl peptidase-IV inhibitors of natural origin (part I): virtual screening and activity assays.

Guasch L, Ojeda MJ, González-Abuín N, Sala E, Cereto-Massagué A, Mulero M, Valls C, Pinent M, Ardévol A, Garcia-Vallvé S, Pujadas G. PLoS One. 2012;7(9):e44971. doi: 10.1371/journal.pone.0044971. Epub 2012 Sep 12.

New adipokines vaspin and omentin. Circulating levels and gene expression in adipose tissue from morbidly obese women.

Auguet T, Quintero Y, Riesco D, Morancho B, Terra X, Crescenti A, Broch M, Aguilar C, Olona M, Porras JA, Hernandez M, Sabench F, del Castillo D, Richart C. BMC Med Genet. 2011 Apr 28;12:60. doi: 10.1186/1471-2350-12-60.

Upregulation of lipocalin 2 in adipose tissues of severely obese women: positive relationship with proinflammatory cytokines.

Auguet T, Quintero Y, Terra X, Martínez S, Lucas A, Pellitero S, Aguilar C, Hernández M, del Castillo D, Richart C. Obesity (Silver Spring). 2011 Dec;19(12):2295-300. doi: 10.1038/oby.2011.61. Epub 2011 Mar 31.

FABP 4 is associated with inflammatory markers and metabolic syndrome in morbidly obese women.

Terra X, Quintero Y, Auguet T, Porras JA, Hernández M, Sabench F, Aguilar C, Luna AM, Del Castillo D, Richart C. Eur J Endocrinol. 2011 Apr;164(4):539-47. doi: 10.1530/EJE-10-1195.

Antioxidant effects of a grapeseed procyanidin extract and oleoyl-estrone in obese Zucker rats.

Castrillejo VM, Romero MM, Esteve M, Ardévol A, Blay M, Bladé C, Arola L, Salvadó MJ. Nutrition. 2011 Nov-Dec;27(11-12):1172-6. doi: 10.1016/j.nut.2010.12.010. Epub 2011 Apr 15.

Adipose triglyceride lipase and hormone-sensitive lipase are involved in fat loss in JunB-deficient mice.

Pinent M, Prokesch A, Hackl H, Voshol PJ, Klatzer A, Walenta E, Panzenboeck U, Kenner L, Trajanoski Z, Hoefler G, Bogner-Strauss JG. Endocrinology. 2011 Jul;152(7):2678-89. doi: 10.1210/en.2010-1477. Epub 2011 May 3.

Identification of human IKK-2 inhibitors of natural origin (part I): modeling of the IKK-2 kinase domain, virtual screening and activity assays.

Sala E, Guasch L, Iwaszkiewicz J, Mulero M, Salvadó MJ, Pinent M, Zoete V, Grosdidier A, Garcia-Vallvé S, Michielin O, Pujadas G. PLoS One. 2011 Feb 24;6(2):e16903. doi: 10.1371/journal.pone.0016903.

Procyanidin dimer B1 and trimer C1 impair inflammatory response signalling in human monocytes.

Terra X, Palozza P, Fernandez-Larrea J, Ardevol A, Blade C, Pujadas G, Salvado J, Arola L, Blay MT. Free Radic Res. 2011 May;45(5):611-9. doi: 10.3109/10715762.2011.564165.

Modulatory effect of grape-seed procyanidins on local and systemic inflammation in diet-induced obesity rats.

Terra X, Pallarés V, Ardèvol A, Bladé C, Fernández-Larrea J, Pujadas G, Salvadó J, Arola L, Blay M. J Nutr Biochem. 2011 Apr;22(4):380-7. doi: 10.1016/j.jnutbio.2010.03.006. Epub 2010 Jul 23.

Dietary catechins and procyanidins modulate zinc homeostasis in human HepG2 cells.

Quesada IM, Bustos M, Blay M, Pujadas G, Ardèvol A, Salvadó MJ, Bladé C, Arola L, Fernández-Larrea J. J Nutr Biochem. 2011 Feb;22(2):153-63. doi: 10.1016/j.jnutbio.2009.12.009. Epub 2010 May 14.

Effects of a grapeseed procyanidin extract (GSPE) on insulin resistance.

Montagut G, Bladé C, Blay M, Fernández-Larrea J, Pujadas G, Salvadó MJ, Arola L, Pinent M, Ardévol A. J Nutr Biochem. 2010 Oct;21(10):961-7. doi: 10.1016/j.jnutbio.2009.08.001. Epub 2009 Dec 4.

Development of a coculture system to evaluate the bioactivity of plant extracts on pancreatic β-cells.

Castell-Auví A, Cedó L, Pallarés V, Blay MT, Pinent M, Motilva MJ, Arola L, Ardévol A. Planta Med. 2010 Oct;76(14):1576-81. doi: 10.1055/s-0029-1241002. Epub 2010 Mar 22.

Oligomers of grape-seed procyanidin extract activate the insulin receptor and key targets of the insulin signaling pathway differently from insulin.

Montagut G, Onnockx S, Vaqué M, Bladé C, Blay M, Fernández-Larrea J, Pujadas G, Salvadó MJ, Arola L, Pirson I, Ardévol A, Pinent M. J Nutr Biochem. 2010 Jun;21(6):476-81. doi: 10.1016/j.jnutbio.2009.02.003. Epub 2009 May 14.

Reconstruction of gene association network reveals a transmembrane protein required for adipogenesis and targeted by PPARγ.

Bogner-Strauss JG, Prokesch A, Sanchez-Cabo F, Rieder D, Hackl H, Duszka K, Krogsdam A, Di Camillo B, Walenta E, Klatzer A, Lass A, Pinent M, Wong WC, Eisenhaber F, Trajanoski Z. Cell Mol Life Sci. 2010 Dec;67(23):4049-64. doi: 10.1007/s00018-010-0424-5. Epub 2010 Jun 15.

Anti-inflammatory profile of FTO gene expression in adipose tissues from morbidly obese women.

Terra X, Auguet T, Porras JA, Quintero Y, Aguilar C, Luna AM, Hernández M, Sabench F, del Castillo D, Richart C. Cell Physiol Biochem. 2010;26(6):1041-50. doi: 10.1159/000323979. Epub 2011 Jan 4.

Apolipoprotein C3 gene variants in nonalcoholic fatty liver disease.

Richart C, Auguet T, Terra X. N Engl J Med. 2010 Jul 8;363(2):193-4; author reply 195. doi: 10.1056/NEJMc1005265.

Grape seed proanthocyanidins correct dyslipidemia associated with a high-fat diet in rats and repress genes controlling lipogenesis and VLDL assembling in liver.

Quesada H, del Bas JM, Pajuelo D, Díaz S, Fernandez-Larrea J, Pinent M, Arola L, Salvadó MJ, Bladé C. Int J Obes (Lond). 2009 Sep;33(9):1007-12. doi: 10.1038/ijo.2009.136. Epub 2009 Jul 7.

Grape-seed procyanidins modulate inflammation on human differentiated adipocytes in vitro.

Chacón MR, Ceperuelo-Mallafré V, Maymó-Masip E, Mateo-Sanz JM, Arola L, Guitiérrez C, Fernandez-Real JM, Ardèvol A, Simón I, Vendrell J. Cytokine. 2009 Aug;47(2):137-42. doi: 10.1016/j.cyto.2009.06.001. Epub 2009 Jun 27.

Dietary procyanidins enhance transcriptional activity of bile acid-activated FXR in vitro and reduce triglyceridemia in vivo in a FXR-dependent manner.

Del Bas JM, Ricketts ML, Vaqué M, Sala E, Quesada H, Ardevol A, Salvadó MJ, Blay M, Arola L, Moore DD, Pujadas G, Fernandez-Larrea J, Bladé C. Mol Nutr Food Res. 2009 Jul;53(7):805-14. doi: 10.1002/mnfr.200800364.

In vivo, in vitro, and in silico studies of Cu/Zn-superoxide dismutase regulation by molecules in grape seed procyanidin extract.

Puiggròs F, Sala E, Vaqué M, Ardévol A, Blay M, Fernández-Larrea J, Arola L, Bladé C, Pujadas G, Salvadó MJ. J Agric Food Chem. 2009 May 13;57(9):3934-42. doi: 10.1021/jf8034868.

Inhibitory effects of grape seed procyanidins on foam cell formation in vitro.

Terra X, Fernández-Larrea J, Pujadas G, Ardèvol A, Bladé C, Salvadó J, Arola L, Blay M. J Agric Food Chem. 2009 Mar 25;57(6):2588-94. doi: 10.1021/jf803450a.

Grape-seed procyanidins prevent low-grade inflammation by modulating cytokine expression in rats fed a high-fat diet.

Terra X, Montagut G, Bustos M, Llopiz N, Ardèvol A, Bladé C, Fernández-Larrea J, Pujadas G, Salvadó J, Arola L, Blay M. J Nutr Biochem. 2009 Mar;20(3):210-8. doi: 10.1016/j.jnutbio.2008.02.005. Epub 2008 Jul 7.

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