Today, two Master students from MoBioFood Research Group, Iris Ginés and Andreu Gual, presented their Master Thesis
General -
Iris explained the results obtained during her stage in our group regarding the effects of a grape-seed proanthocyanidin extract on intestinal inflammation, oxidative stress and barrier function in rats fed a cafeteria diet during 18 weeks. She found that a chronic supplementation with dietary proanthocyanidins protects from diet-induced intestinal alterations in obese rats.
Andreu showed his results regarding the effects of the proanthocyanidin extract on lipid metabolism. The results indicated that chronic and chronic-preventive nature of GSPE administration against obesity has positive effects in the modulation of lipid oxidation, showing evidence of further degradation of lipids in response to the treatment in a different manner according to the study conditions. In the chronic model lipid oxidation in subcutaneous adipose tissue is increased, while in the chronic-preventive model lipid oxidation is increased in the liver.